Aerosols play important roles in the transmission of airborne pathogens between an infected host and a susceptible individual. CDT projects are exploring the links between aerosol microphysics and airborne pathogen survival, the interactions with ambient environmental aerosol and pollution, and new approaches to model aerosol transport and deposition. They are also developing new tools to sample and detect airborne biological aerosol and pathogens.
Comparing the Airborne Survival of Enveloped and Non-enveloped Viruses
Respiratory aerosol particles transmit pathogens such as SARS-CoV-2 between infected and susceptible individuals. While airborne, the infectivity of viruses declines at a rate that is influenced by the microphysical processes occurring in the aerosol (e.g. water evaporation). This project will compare the airborne survival of enveloped and non-enveloped viruses.
Digital Microfluidic Lab-on-a-chip for multiplex detection of biomarkers in exhaled breath
Exhaled aerosols contain precious information on lung health, which could inform diagnosis and therapies and help saving lives. This project will combine emerging microfluidic and lab-on-a-chip technologies to create a portable and fully automated Lab-on-a-chip for detection of multiple disease biomarkers in exhaled aerosols.
Interaction of SARS – CoV2 and Influenza Viruses with Particulate Matter Air Pollution
Higher transmission rates and worsening of health outcome from exposure to SARS-CoV-2 and influenza has been linked to high levels of pollution exposure. This PhD will characterise whether the airborne spread, transmission and infectivity of influenza virus and SARS-CoV-2 increases by hitchhiking on to particulate matter pollution.
The structure of exhaled droplets and aerosols
As we know only too well many diseases are transmitted via exhaled droplets/aerosols. Despite their importance we don’t currently have a good understanding of their composition, drying behaviour or structure. This project will develop techniques to characterise these aerosols and, by drying droplets of synthetic respiratory fluid, investigate how the structures are formed.
Modelling of airborne transmissions of respiratory droplets containing COVID-19 virus
COVID-19 virus spreads by the inhalation of “airborne” microscopic respiratory droplets and after evaporation by aerosols of their solid residues. In this project, a first-principle model of the evaporation and subsequent dispersion of the aerosol in air within a room will be developed to provide effective guidelines for safe and social distancing.
Exhalation, inhalation dynamics of aerosol and airborne transmission disease
Understanding the impact that airborne transport has on pathogens and the influence of environmental conditions on pathogen survival can inform the implementation of strategies to mitigate the spread of diseases such as COVID. However, from the point of generation to exhalation and inhalation dynamic of aerosol is poorly understood.
Replication and modelling of infectious respiratory droplets in humans and animals
Using novel aerosol technologies with human and animal samples and pathogens for the first time, the project aims to understand how the changing environment of respiratory droplets influences pathogen viability and transmission. Such understanding through this interdisciplinary approach could aid development of strategies to prevent the spread of respiratory infections.
Collection methods for early detection of airborne viruses
Airborne aerosols are a primary transport mechanism for many diseases. Through experimentation, computational modelling and engineering prototyping, you will investigate aerosol capture mechanisms for effective real-time monitoring of disease transportation. This will include fundamental studies on the properties of the collected material and the principles of aerosol collection.
EPSRC CDT in Aerosol Science
University of Bristol
School of Chemistry
Bristol, BS8 1TS
Sign up to receive monthly news and updates from the CDT in Aerosol Science, as well as events, training and research webinars.